{"record":{"author":{"account_ref":null,"orcid":null},"builds_on":[],"content_schema":"pubphys.content.topic/1","content_sha256":"cb221478006c64e7eb738d4ab54a3e8bca7302a2e76dfd2abbb74d9a817692da","created":"2026-10-03T07:17:50Z","files":[],"origin":{"assisted_by":[],"kind":"seed"},"parents":[],"salt":"480c8f22ffcd8adcb45739cfc0f66806a1448dc20ef368ac7f62830b4f1f38ca","schema":"pubphys.record/2","site":"pubphys.com","target":null,"type":"topic"},"content":{"external_id":"bio.condensates","field":"bio","n":"1","review_cite":"Clifford P. Brangwynne, Peter Tompa, Rohit V. Pappu, Polymer physics of intracellular phase transitions, Nature Physics, 2015","review_link":"https://doi.org/10.1038/nphys3532","review_verified":"true","summary":"Cells contain droplets without membranes, called condensates, that form when certain proteins and RNAs separate from the surrounding fluid, much as oil separates from water. Many of these proteins are floppy chains with no fixed shape, and how their sequence sets droplet behavior, and what the droplets do for the cell, are open.","title":"Biomolecular condensates and intrinsically disordered proteins","topic_ref":null,"why":"Condensates organize cell chemistry, and their hardening into solids is linked to the motor-neuron disease ALS and other neurodegenerative diseases."},"attested":{"attestation":{"batch":null,"client_id":null,"id_token_sha256":null,"kind":"platform"},"record_hash":"543417a9e932d4539361d9de3ab0b3df002be16d6b1f7e3413f005ca5af8568d","schema":"pubphys.attested/1"},"envelope":{"attested_hash":"85e9f80cbd168f6e9688ecb991cb73a2172d93f284e93a6184fa02ce915a189b","platform_signature":{"key_id":"c6afc19b31429869751f06879c75cd64ea92654423d15b44be775bf1310a60da","sig":"MfAoTZF_-qdHyqTAMQoNML7Au-xUVo8E-3f1lFuNmhyG3vqh1ZAfkeq13C3CoZShqRlqV6ljyT2Blj5Bt8SuCQ"},"schema":"pubphys.envelope/1"},"record_hash":"543417a9e932d4539361d9de3ab0b3df002be16d6b1f7e3413f005ca5af8568d","leaf_index":86}