{"record":{"author":{"account_ref":null,"orcid":null},"builds_on":[],"content_schema":"pubphys.content.revision/1","content_sha256":"5ca5374ab64a208e8f58d78dda448558687d50d5637a3df94612b48a08f67ff7","created":"2026-10-03T07:18:06Z","files":[],"origin":{"assisted_by":[],"kind":"seed"},"parents":["5475cf5dc5b1a72283d26dc95dc6e00d7ea4e00096a7c6492e409a1816eeb011"],"salt":"931a6eed6fb9a6361e1f053e62af3a45bda4f2a1deb41cf1443bf09d2ef12649","schema":"pubphys.record/2","site":"pubphys.com","target":null,"type":"revision"},"content":{"answer_type":"value","assisted_by":[],"external_id":"med.microdosimetry.radiolysis-chemistry","kind":"well-posed","literature_status":"open","n":"1","parents":[],"plain":"Water split by radiation produces reactive fragments whose numbers change over nanoseconds to seconds. Current models stop too early to describe what reaches biological targets.","posed_since":"1980","precise":"Extend inhomogeneous radiation chemistry past $1\\,\\mathrm{microsecond}$ into the homogeneous regime in realistic cellular media, including oxygen, scavengers at millimolar concentration, lipid and protein targets, and track overlap at high dose rate. Required outputs: yields $G$ of hydroxyl radical, hydrated electron, hydroperoxyl, hydrogen peroxide and organic peroxyl species versus time, LET and dose rate. An answer is a validated kinetic scheme over $10^{-12}\\ \\text{to}\\ 10\\,\\mathrm{s}$.","problem_ref":null,"references":"","settled_by":"Time-resolved scavenger and probe measurements across LET and dose rate reproduced by one kinetic model without per-case refitting.","status_note":"Interest grew after 2019 because the FLASH effect depends on exactly this regime.","title":"Radiation chemistry beyond the homogeneous stage","topic_ref":"72f2e40584d11439e863e00d2c447e82cf67118c73a199c7fc6c190acf8de8c7"},"attested":{"attestation":{"batch":null,"client_id":null,"id_token_sha256":null,"kind":"platform"},"record_hash":"a8113b716cdcf2d3aff4b8c9a56a726a7ee7a8d2e61a60b45b8462c480f5368a","schema":"pubphys.attested/1"},"envelope":{"attested_hash":"9fa1667a62fe5e5a94c62ff12782ca624f14b00a831de4945a2e34775020cbca","platform_signature":{"key_id":"c6afc19b31429869751f06879c75cd64ea92654423d15b44be775bf1310a60da","sig":"XYKdxfmjVQXfDn_-uOkaqlHflxbauvfo_6yIlACwjp3_FjON3VeWvqbLonnqJgZ2U3xUIRWe1ZshJzQfOWF6DA"},"schema":"pubphys.envelope/1"},"record_hash":"a8113b716cdcf2d3aff4b8c9a56a726a7ee7a8d2e61a60b45b8462c480f5368a","leaf_index":1707}