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A working scanner that does this accurately in a patient does not exist.","posed_since":"","precise":"Image the B-10 concentration in tissue during neutron irradiation through the 478 keV gamma line from the Li-7 excited state, with 10 percent accuracy in concentration, about 5 mm spatial resolution and a frame time of minutes, against the intense background of 2.2 MeV hydrogen-capture gammas and neutron-induced detector activation. An answer is a demonstrated detector and reconstruction method with these figures in a patient-sized phantom.","problem_ref":null,"references":"","settled_by":"Phantom measurements with known boron distributions in a clinical epithermal beam showing the stated concentration accuracy and resolution.","status_note":"Prompt-gamma tomography prototypes for neutron capture therapy were in development without clinical use.","title":"Real-time imaging of boron concentration during 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