{"record":{"author":{"account_ref":null,"orcid":null},"builds_on":[],"content_schema":"pubphys.content.revision/1","content_sha256":"1bd2795e39fb06eabf5c0962f6ab0fb2dabf1efea606e175518fb144c4c3688e","created":"2026-10-03T07:17:58Z","files":[],"origin":{"assisted_by":[],"kind":"seed"},"parents":["42a86c776025a01a20575a017e02736410c80b86057d25a2025fe85a8c6bf16c","5475cf5dc5b1a72283d26dc95dc6e00d7ea4e00096a7c6492e409a1816eeb011","8883d21a923f0f2fc5804c7ed99683b74bb6717102f5b0726f25e7f03972a589"],"salt":"41a51a309bf776e1352a408b5e9b913a244934bfeaa43d3f9379c1ab6efce9a2","schema":"pubphys.record/2","site":"pubphys.com","target":null,"type":"revision"},"content":{"answer_type":"yes-no","assisted_by":[],"external_id":"chem.polaritonic-chemistry.deprotection-reproducibility","kind":"well-posed","literature_status":"contested","n":"1","parents":[{"note":"Silane deprotection is the flagship case of reproducibility of cavity rate claims","parent_revision":"42a86c776025a01a20575a017e02736410c80b86057d25a2025fe85a8c6bf16c","relation":"special_case"},{"note":"","parent_revision":"8883d21a923f0f2fc5804c7ed99683b74bb6717102f5b0726f25e7f03972a589","relation":"special_case"}],"plain":"The first widely cited claim of a dark cavity effect concerned a reaction that removes a silicon-containing group from a molecule. Independent groups have reported different results for the same reaction.","posed_since":"2016","precise":"For the fluoride-induced desilylation of 1-phenyl-2-trimethylsilylacetylene in a Fabry-Perot cavity tuned to the Si-C stretch near $860\\ \\mathrm{cm}^{-1}$ or the Si-CH3 deformation near $1250\\ \\mathrm{cm}^{-1}$, determine whether the rate constant changes relative to detuned cavities by more than the combined experimental error, under controlled temperature and identical sample preparation. An answer is a yes or no from multi-laboratory measurements with shared protocols.","problem_ref":null,"references":"","settled_by":"A round-robin measurement across several laboratories with identical cavities, reagents and temperature control.","status_note":"The original 2016 report (Thomas et al., Angew. Chem.) found a slowdown of several times; a 2021 replication attempt (Imperatore, Asbury, Giebink, J. Chem. Phys., https://doi.org/10.1063/5.0046307) found no cavity effect beyond error.","title":"Reproducibility of the cavity-modified silane deprotection rate","topic_ref":"a1800d58731adf7edb05cc3f1a2db4d47371dec4cc339e0c64df5cda73c94331"},"attested":{"attestation":{"batch":null,"client_id":null,"id_token_sha256":null,"kind":"platform"},"record_hash":"f54906a64a1556474a030a8fbe33a293f9ef68a7a521bbd2263b1b5c21231cc6","schema":"pubphys.attested/1"},"envelope":{"attested_hash":"a0a6d807cc9684d01a38651f47e909de13cfca6db34f8a142306bfb1469ece06","platform_signature":{"key_id":"c6afc19b31429869751f06879c75cd64ea92654423d15b44be775bf1310a60da","sig":"lfzgBDYM7ruFe4wDcn6oyFiHCSRaxkrV5XkEPi8LfZIS2mlrn-v6gFjHhduWoqY-nWg7TYlDGojzqikT0OmxDw"},"schema":"pubphys.envelope/1"},"record_hash":"f54906a64a1556474a030a8fbe33a293f9ef68a7a521bbd2263b1b5c21231cc6","leaf_index":887}