{"record":{"author":{"account_ref":null,"orcid":null},"builds_on":[],"content_schema":"pubphys.content.topic/1","content_sha256":"440c2432a811a599f2b7075f2ba4ca60076d566753659563516b178530eb175e","created":"2026-10-03T07:17:50Z","files":[],"origin":{"assisted_by":[],"kind":"seed"},"parents":[],"salt":"1292cff235510b87f4ebeaad9e22b259723094ad7c2d1df172035b353ee51722","schema":"pubphys.record/2","site":"pubphys.com","target":null,"type":"topic"},"content":{"external_id":"bio.accuracy-timekeeping","field":"bio","n":"1","review_cite":"Andre C. Barato, Udo Seifert, Thermodynamic Uncertainty Relation for Biomolecular Processes, Physical Review Letters, 2015","review_link":"https://doi.org/10.1103/PhysRevLett.114.158101","review_verified":"true","summary":"Cells copy DNA, build proteins and keep time with error rates far below what chemical equilibrium would allow, by burning fuel such as ATP. Physics asks what minimum fuel cost a given accuracy or timing precision requires, and how close cells come to it.","title":"Energy cost of biological accuracy and timekeeping","topic_ref":null,"why":"These costs set basic limits on the speed, fidelity and energy budget of every living cell."},"attested":{"attestation":{"batch":null,"client_id":null,"id_token_sha256":null,"kind":"platform"},"record_hash":"fa5a2b5a5ef38544b68e067ac335f685369c4bef3348616fa71997a19f8444ca","schema":"pubphys.attested/1"},"envelope":{"attested_hash":"2e3024f971bb7c717981743ab27ca879f228184c4705ddf1fb135a69c54391f8","platform_signature":{"key_id":"c6afc19b31429869751f06879c75cd64ea92654423d15b44be775bf1310a60da","sig":"XfKyu_pK897nucYYmUN0siK799tyF7i3URmiyd2YTIqFKdCXPzSHxiiUlgt51cmZdaVNVzyqOkZ34mhecWMYCA"},"schema":"pubphys.envelope/1"},"record_hash":"fa5a2b5a5ef38544b68e067ac335f685369c4bef3348616fa71997a19f8444ca","leaf_index":79}