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A test of understanding is to predict these flows, and the resulting shapes, from the measured pattern of motor activity alone.","posed_since":"2018","precise":"For whole-embryo morphogenesis (e.g., Drosophila gastrulation and germ-band extension), formulate a continuum model (thin viscous shell with active stress proportional to measured myosin density) whose velocity field v(x, t) matches light-sheet tissue-flow data with correlation above 0.9 over the full process, including later stages with cell intercalation and tissue folding, using one parameter set. Answer: yes or no, with the model and its quantitative fit.","problem_ref":null,"references":"","settled_by":"A fixed-parameter model fit to whole-embryo myosin and flow data across all gastrulation stages, validated on myosin-perturbed mutants.","status_note":"A 2018 study (Streichan and co-workers) predicted early Drosophila gastrulation flow from the myosin pattern with a Stokes-flow model; later stages and folding remain open.","title":"Predict embryo-scale tissue flow from measured motor 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