{"record":{"author":{"account_ref":null,"orcid":null},"builds_on":[],"content_schema":"pubphys.content.revision/1","content_sha256":"f430295b7583201d99b1cf1e43db2c3c1e347c221b04a9f734658563b97c2f15","created":"2026-10-03T07:17:58Z","files":[],"origin":{"assisted_by":[],"kind":"seed"},"parents":["5475cf5dc5b1a72283d26dc95dc6e00d7ea4e00096a7c6492e409a1816eeb011"],"salt":"a9fcefed0ce20876a7d6063d042f94b3a7ce37b0d69867c719bbf34354bda0b6","schema":"pubphys.record/2","site":"pubphys.com","target":null,"type":"revision"},"content":{"answer_type":"yes-no","assisted_by":[],"external_id":"chem.cavity-chemistry.single-molecule-coupling","kind":"well-posed","literature_status":"partially-resolved","n":"1","parents":[],"plain":"If a single molecule could mix strongly with light, cavity effects on chemistry could be tested without the problem of sharing among many molecules. Tiny gaps between metal particles (plasmonic nanocavities) have been reported to reach this regime for electronic states of a single molecule, but proof is debated, and for vibrations it is far out of reach.","posed_since":"","precise":"In plasmonic nanocavities (gap below 1 nm) at 300 K, establish whether a single molecule reaches strong coupling, meaning a Rabi splitting 2g exceeding the mean of the plasmon and emitter linewidths with clear single-emitter evidence such as photon antibunching or a splitting that does not scale with molecule number, first for an electronic transition and then for a vibrational transition. Then determine whether single-molecule strong coupling changes a measured photochemical or thermal reaction rate of that molecule.","problem_ref":null,"references":"","settled_by":"Single-emitter spectroscopy with antibunching and number-calibrated splitting in a nanocavity, followed by single-molecule reaction kinetics under resonant and detuned conditions.","status_note":"Electronic single-molecule strong coupling at room temperature was reported in plasmonic nanocavities in 2016 (Chikkaraddy et al., Nature, https://doi.org/10.1038/nature17974), with the attribution still debated; single-molecule vibrational strong coupling and its effect on reactivity have not been demonstrated.","title":"Room-temperature strong coupling and chemistry of single molecules","topic_ref":"a1800d58731adf7edb05cc3f1a2db4d47371dec4cc339e0c64df5cda73c94331"},"attested":{"attestation":{"batch":null,"client_id":null,"id_token_sha256":null,"kind":"platform"},"record_hash":"fe405e659622af0fd760266b0bba32cbb911ab4934378f48f513f70cce7200c8","schema":"pubphys.attested/1"},"envelope":{"attested_hash":"adf858bd746c1c02993601918d55e62793dc5c584c0cf6dc835d5d4c25d65246","platform_signature":{"key_id":"c6afc19b31429869751f06879c75cd64ea92654423d15b44be775bf1310a60da","sig":"NPRcgRShVwGJpv4hK3btYlDYTo57y620w4QmJB5CWmStXBG-VGzt6gxwak-GRrvA2_ziluFCe6ue4qG1nNXaAQ"},"schema":"pubphys.envelope/1"},"record_hash":"fe405e659622af0fd760266b0bba32cbb911ab4934378f48f513f70cce7200c8","leaf_index":852}