MEDTopic
Spatially fractionated and microbeam radiotherapy
If radiation is delivered in a comb of narrow beams separated by unirradiated gaps, healthy tissue tolerates doses that would otherwise destroy it, while tumours still respond. The reason is not understood and the best comb spacing is unknown.
Why it matters
The tolerance gain is large, so settling the physics could raise deliverable tumour dose substantially.
Review
Yan, Khan, Wu, Simone, Fan, Gressen, Zhang, Limoli, Bahig, Tubin and Mourad, Spatially fractionated radiation therapy: History, present and the future, Clinical and Translational Radiation Oncology, 2020. https://doi.org/10.1016/j.ctro.2019.10.004 reference checked
Proof
- Signed record
- 309568a913ee…
- Public log
- Entry 279, in checkpoint 2,123
- Bitcoin date
- Block 969,698, 2026-10-03